Vice President Clinical Development

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Vice President Clinical Development


POSITION DESCRIPTION

Position          Vice President Clinical Development
Company        resTORbio, Inc.
Location         Boston, MA
Website          https://www.restorbio.com/


COMPANY BACKGROUND

resTORbio, Inc. (NASDAQ: TORC, $482M mkt cap) is a clinical-stage biopharmaceutical company focused on helping people live healthier longer through the development and commercialization of novel therapeutics for the treatment of aging-related diseases. resTORbio’s lead program is targeting the selective inhibition of TORC1 - an evolutionary conserved pathway that contributes to the decline in function of multiple organ systems, including the immune, cardiac and neurologic systems. resTORbio program has demonstrated in several clinical trials, including a randomized, placebo-controlled trial, the potential to treat multiple diseases of aging for which there are no approved therapies. RTB101, resTORbio’s lead drug candidate is a selective, orally administered, TORC1 inhibitor currently being tested in a Phase 2b clinical trial as a first in-class immunotherapy for reducing the incidence of respiratory tract infections in the elderly by enhancing the function of the immune system. The company expects to develop RTB101 for additional aging-related indications such as heart failure or neurodegenerative diseases.


ROLE: VICE PRESIDENT CLINICAL DEVELOPMENT

  • Responsible for the overall direction, planning, execution and interpretation of the clinical program.
  • Provide leadership to the clinical team and ensure that operational aspects of clinical studies are appropriately implemented to support scientific and medical objectives. Ensure high quality timely deliverables on clinical studies.
  • Evaluate preclinical data and determine whether and how it can be translated to humans.
  • Serve as a liaison with KOLs, PIs, in the academic / medical community.
  • Responsible for interpreting and communicating clinical results to the investment community and BOD.
  • Represent ResTORbio to medical communities and regulatory agencies across various therapeutic areas.
  • Collaborate with executive team to determine clinical goals.
  • Lead the clinical team to ensure protocols are scientifically sound and designed to answer appropriate questions.
  • Motivated to work in a fast-paced, highly accountable, small company environment. A "can do" and collegial professional who leads through influence and interpersonal skills.
  • Collaborate with regulatory colleagues to provide appropriate clinical input on all regulatory documents filed both in the United States and abroad.
  • Review/Edit CSRs, slide presentations of clinical data, manuscripts, abstracts, posters and oral presentations for accuracy, content and messaging.

*additional duties and responsibilities not listed here may be required 


PROFESSIONAL EXPERIENCE / QUALIFICATIONS

  • 2+ years of clinical development experience within the Pharmaceutical or Biotechnology setting; 5+ years of clinical experience.
  • Experience running a basic science lab (preferred).
  • Excellent written and verbal communications skills and ability to work in a collaborative team environment.

EDUCATION

M.D.


COMPENSATION

An attractive compensation package commensurate with this senior leadership role will be provided.


HIRING  EXECUTIVE PROFILE

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Joan Mannick, M.D.
Co-Founder, Chief Medical Officer

Dr. Mannick is Co-Founder and Chief Medical Officer of resTORbio. Prior to joining resTORbio, Dr. Mannick was Executive Director in the New Indications Discovery Unit of the Novartis Institutes of Biomedical Research where Dr. Mannick led the clinical program at Novartis that targets pathways regulating aging to treat aging-related conditions. Prior to joining Novartis in 2010, Dr. Mannick was a Medical Director at Genzyme working in multiple therapeutic areas. Prior to Genzyme, Dr. Mannick was a faculty member at Harvard Medical School and University of Massachusetts Medical School. Her NIH-sponsored laboratory focused on the role of protein S-nitrosylation in physiology and pathophysiology. Dr. Mannick received her A.B. from Harvard College and her M.D. from Harvard Medical School. She completed her residency in Internal Medicine at Brigham and Women’s Hospital and an Infectious Disease fellowship as part of the Harvard Combined Infectious Disease Program.


TO APPLY PLEASE CONTACT A KLEIN HERSH REPRESENTATIVE

Jesse Klein
Managing Partner
220 Gibraltar Road, Ste 150
Horsham, PA 19044
Phone: 267-948-1438
Email: jklein@kleinhersh.com

Jared Kaleck
Client Partner
220 Gibraltar Road, Ste 150
Horsham, PA 19044
Phone: 215-830-9229
Email: jkaleck@kleinhersh.com

Jeff Azarva
Director, Physician Recruitment
220 Gibraltar Road, Ste 150
Horsham, PA 19044
Phone: 267-948-1439
Email: jazarva@kleinhersh.com

Ethan Schwartz
Director, Physician Recruitment
220 Gibraltar Road, Ste 150
Horsham, PA 19044
Phone: 267-948-1438
Email: ESchwartz@kleinhersh.com

Matt Taitelman
Director, Physician Recruitment
220 Gibraltar Road, Ste
150 Horsham, PA 19044
Phone: 267-948-1445
Email: mtaitelman@kleinhersh.com

Ilysa Shorr
Physician Recruitment – (Support)
220 Gibraltar Road, Ste 150
Horsham, PA 19044
Phone: 267-948-1434
Email: ishorr@kleinhersh.com